Could Arg cause Disease progression? - a phase IV clinical study (2025)

Summary:

Disease progression is reported as a side effect among people who take Arg (l - arginine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lutathera, and have Pancreatic neuroendocrine tumor.

The phase IV clinical study analyzes which people have Disease progression when taking Arg, including time on the drug, (if applicable) gender, age, co-used drugs and more. It is created by eHealthMe based on reports of 2,399 people who have side effects when taking Arg from the FDA, and is updated regularly.

With medical big data and AI/ML algorithms, eHealthMe runs millions of phase IV clinical trials to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 700+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 30, 2024

2,399 people reported to have side effects when taking Arg. Among them, 21 people (0.88%) have Disease progression.

What is Arg?

Arg has active ingredients of l - arginine. eHealthMe is studying from 2,660 Arg users for the drug's side effects, drug interactions, effectiveness and more. Check Arg in the real world.

Number of Arg and Disease progression reports submitted per year:

How long have people been on Arg when they have Disease progression? *

• < 1 month: 100 %
• 1 - 6 months: 0.0 %
• 6 - 12 months: 0.0 %
• 1 - 2 years: 0.0 %
• 2 - 5 years: 0.0 %
• 5 - 10 years: 0.0 %
• 10+ years: 0.0 %

What is the gender of people who have Disease progression when taking Arg? *

• female: 50 %
• male: 50 %

What is the age of people who have Disease progression when taking Arg? *

• 0-1: 11.11 %
• 2-9: 0.0 %
• 10-19: 0.0 %
• 20-29: 0.0 %
• 30-39: 5.56 %
• 40-49: 11.11 %
• 50-59: 0.0 %
• 60+: 72.22 %

What are other drugs people take besides Arg? *

1. Lutathera: 6 people, 28.57%
2. Calcium: 4 people, 19.05%
3. Vitamin D3: 3 people, 14.29%
4. Lysine: 3 people, 14.29%
5. Potassium: 3 people, 14.29%
6. Nexium: 2 people, 9.52%
7. Buphenyl: 2 people, 9.52%
8. Glucosamine: 2 people, 9.52%
9. Chromium Picolinate: 2 people, 9.52%
10. Lecithin: 2 people, 9.52%

What are other side effects people have besides Disease progression? *

1. Thrombocytopenia (decrease of platelets in blood): 7 people, 33.33%
2. Nasopharyngitis (inflammation of the nasopharynx): 4 people, 19.05%
3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 14.29%
4. Hearing Loss: 2 people, 9.52%
5. Myelosuppression (a decrease in the production of blood cells): 2 people, 9.52%
6. Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 2 people, 9.52%
7. Weakness: 2 people, 9.52%
8. Malaise (a feeling of general discomfort or uneasiness): 2 people, 9.52%
9. Itching: 2 people, 9.52%
10. Infection: 2 people, 9.52%

What are the existing conditions these people have? *

1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 14.29%
2. Pancreatic Neuroendocrine Tumor: 3 people, 14.29%
3. Thyroid Diseases: 2 people, 9.52%
4. Neuroendocrine Tumor: 2 people, 9.52%
5. Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 2 people, 9.52%
6. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 2 people, 9.52%
7. Malignant Peritoneal Neoplasm (cancer tumour of peritoneum): 2 people, 9.52%
8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 9.52%
9. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 9.52%
10. Renal Cell Carcinoma (a kidney cancer): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Arg and have Disease progression?

- Check whether Disease progression is associated with a drug or a condition

- Predict drug outcomes for up to one year with AI

How the study uses the data?

The study uses data from the FDA. It is based on l - arginine (the active ingredients of Arg) and Arg (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies are listed below in case you need more information:

Effectiveness of, long term effects of, and alternative drugs to Arg:

• Arg (2,660 reports)

Disease progression treatments and more:

• Disease progression (115,298 reports)

How severe was Disease progression and when was it recovered:

• Disease progression in Arg

Browse all side effects of Arg:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Disease progression:

• Disease progression (1,847 drugs)

Browse all the conditions that are associated with Disease progression:

• Disease progression (2,179 conditions)

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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